Formed from Nueces County; created February 10, 1848; organized August 7, 1848. Named for Dr. James Harper Starr 1809-1890; pioneer Texas surgeon and Indian fighter, located at Nacogdoches in 1837; Secretary of the Treasury of the Republic of Texas 1839-1840; Assistant Postmaster General of the Confederacy. Rio Grande City, the county seat.
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